Acinetobacter is a gramnegative bacterium commonly found in soil and water. Pdf molecular mechanisms associated with nosocomial. Garzagonzalezgenetic characterisation of drug resistance and clonal dynamics of acinetobacter baumannii in a hospital setting in mexico. The aims of this study were to investigate the antimicrobial resistance profile, the clonal relatedness. Acinetobacter baumannii infection what you need to know. Molecular mechanisms associated with nosocomial carbapenemresistant acinetobacter baumannii in mexico article pdf available in archives of medical research 457 november 2014 with 9 reads. It can be an opportunistic pathogen in humans, affecting people with compromised immune systems, and is becoming increasingly important as a hospitalderived infection. It resists many classes of antibiotics by virtue of chromosomemediated genetic elements on. Acinetobacter baumannii, a nonfermenter gramnegative coccobacillus, was considered a lowcategory pathogen in the past, but has now emerged as a leading cause of hospital and communityacquired infections. En dos estudios europeos, acinetobacter lwoffi fue la especie mas predominante encontrada en la piel de individuos sanos, con tasas de portadores de entre el 29 y el 58%, mientras que otras especies de acinetobacter, incluyendo acinetobacter junii, acinetobacter johnsonii, acinetobacter radiorresis. Carbapenemase genes, active efflux mechanism to imipenem and meropenem and outer membrane proteins profile were analyzed to. Acinetobacter baumannii ist ein gramnegatives, aerobes bakterium.
It typically infects people inside a healthcare facility doctors refer to these as nosocomial infections. Characterization of a hospital outbreak of imipenemresistant acinetobacter baumannii by phenotypic and genotypic typing methods. It is a frequent cause of pneumonia and septicemia in immunocompromised patients. Frontiers carbapenemresistant acinetobacter baumannii. Acinetobacter baumannii is one of the most important nosocomial pathogens distributed worldwide.
Characterization of these species and of particular strains is a priority for the establishment of diagnostic tests and preventive procedures. Virulence profiles and innate immune responses against highly lethal, multidrugresistant nosocomial isolates of acinetobacter baumannii from a tertiary care hospital in mexico. Due to its multidrugresistance and the propensity for the epidemic spread, the world health organization includes this bacterium as a priority health issue for development of new antibiotics. Acinetobacter baumannii can cause infections in the blood, urinary tract, and lungs pneumonia, or in wounds in other parts of the body. While other species of the genus acinetobacter are often found in. Acinetobacter baumannii is a bacterium that can cause a range of diseases.
An acinetobacter baumannii infection is caused by the acinetobacter baumannii bacteria. A centers for disease control and prevention cdc report, antimicrobial resistance threats in. Acinetobacter isolates often demonstrate resistance to multiple classes of antimicrobial drugs, leading to treatment challenges. Acinetobacter spp aspectos microbiologicos, clinicos y. Antibioticresistant acinetobacter baumannii increasing. Carbapenemresistant acinetobacter baumannii in three. It may also cause urinary tract and wound infections.
Antibioticresistant infectious bacteria currently imply a high risk and therefore constitute a strong challenge when treating patients in hospital settings. Healthcare provider information sheet for acinetobacter. Acinetobacter baumannii is a cause of healthcareassociated infections. Acinetobacter baumannii is a typically short, almost round, rodshaped coccobacillus gramnegative bacterium. The relevance of acinetobacter baumannii as a problematic microorganism in inpatient. Acinetobacter baumannii is an opportunistic bacterial pathogen primarily associated with hospitalacquired infections. Antimicrobial susceptibility of acinetobacter baumannii. Carbapenemnonsusceptible acinetobacter baumannii, 8 us. It can be spread by direct contact and may be found on skin or in food, water, or soil. Acinetobacter baumannii maintains its virulence after long. In addition to causing severe disease in hospitalized patients, a. Virulence profiles and innate immune responses were studied in acinetobacter baumannii from nosocomial infections collected over one year in a tertiary care hospital in mexico. It can cause serious infections in the lungs, blood, and brain.